Comparison of the value of PCNA and Ki-67 as markers of cell proliferation in ameloblastic tumors.
Resumen
OBJECTIVES: The aim of this study was to compare among PCNAand Ki-67 as the most reliable immunohistochemical marker for evaluating cell proliferation in ameloblastic tumors. STUDY DESIGN: Observational, retrospective, and descriptive study of a large series of ameloblastic tumors, composed of 161 ameloblastomas and four ameloblastic carcinomas, to determine and compare PCNA and Ki-67 expression using immunohistochemistry techniques. RESULTS: When analyzing Ki-67 positivity, the desmoplastic ameloblastoma demonstrated a significantly lower proliferation rate (1.9 percent) compared with the solid/multicystic and unicystic ameloblastomas and ameloblastic carcinomas (p
Descriptores DECS
AMELOBLASTOMA^sEtiología; PROLIFERACION DE CELULAS; ESTUDIO COMPARATIVO; NEOPLASMAS DE LA BOCA^sPatología; MARCADORES BIOLOGICOS; ANTINGENO NUCLEAR DE CELULA EN PROLIFERACION; MARCADORES BIOLOGICOS; ANTINGENO KI-67
